SERPINB6

Across TCGA cell cohorts, SERPINB6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,146 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SERPINB6-associated GO terms across cancer lineages are Regulation of mononuclear cell migration, Positive regulation of endocytosis, and Regulation of interleukin-6-mediated signaling pathway. Each is linked with SERPINB6 in more than 10 cancer types. Because this analysis shows association rather than direction, both SERPINB6-to-partner and partner-to-SERPINB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mononuclear cell migration grouped by SERPINB6-low versus SERPINB6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB6→partner) and Y-score (partner→SERPINB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of mononuclear cell migration →	+0.151	+2.311	<.001	<.001	3	11
BONE	Positive regulation of endocytosis →	+0.067	+1.357	<.001	.006	3	11
BONE	Regulation of interleukin-6-mediated signaling pathway →	+0.348	+2.298	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Positive regulation of miRNA processing →	+0.208	+2.455	<.001	<.001	3	10
BONE	Positive regulation of interleukin-6-mediated signaling pathway →	+1.114	+2.138	<.001	<.001	3	9
BONE	Epiboly involved in wound healing →	+0.145	+1.769	.003	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,146 associations by consensus.

Regulation of mononuclear cell migration by SERPINB6 expression — BONE

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