Across TCGA patient cohorts, SERPINB5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,164 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERPINB5-associated proteins across cancer lineages are TRIM29, TRIM29_S21, and TRIM29_S489. Each is linked with SERPINB5 in more than 5 cancer types. Because this analysis shows association rather than direction, both SERPINB5-to-partner and partner-to-SERPINB5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB5→partner) and Y-score (partner→SERPINB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TRIM29 →	+1.424	+2.115	<.001	<.001	3	6
BRCA	TRIM29_S21 →	+1.564	+2.009	<.001	<.001	3	6
BRCA	TRIM29_S489 →	+1.361	+1.916	<.001	<.001	3	6
HNSC	KRT16 →	+1.229	+0.998	<.001	.002	3	6
HNSC	VPS4B →	+0.341	+1.378	<.001	<.001	3	5
LUAD	PLEKHG3_S76 →	+1.020	+1.832	.006	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,164 associations by consensus.

Exploration

SERPINB5 survival (RNA) · tumor vs normal (RNA) · all SERPINB5 data types