Across TCGA patient cohorts, SERPINB5 mutation is significantly associated with the RNA expression of many other genes, with 2,842 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINB5-associated genes across cancer lineages are MIR615, ATP2A1-AS1, and RN7SL690P. Each is linked with SERPINB5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINB5-to-partner and partner-to-SERPINB5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB5→partner) and Y-score (partner→SERPINB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR615 →	+0.992	+5.693	<.001	.003	3	3
SKCM	ATP2A1-AS1 →	+0.762	+2.594	.002	.006	3	2
SKCM	RN7SL690P →	+0.078	+3.312	<.001	.001	3	2
SKCM	LINC02841 →	+0.020	+4.528	<.001	.003	3	2
SKCM	CEP128 →	+0.563	+3.497	<.001	.002	3	2
SKCM	NSMCE4A →	+0.549	+3.813	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,842 associations by consensus.

Exploration

SERPINB5 survival (RNA) · tumor vs normal (RNA) · all SERPINB5 data types