Across TCGA cell cohorts, SERPINB5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,544 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SERPINB5-associated GO terms across cancer lineages are Epidermis development, Desmosome organization, and Bundle of His cell to Purkinje myocyte communication. Each is linked with SERPINB5 in more than 10 cancer types. Because this analysis shows association rather than direction, both SERPINB5-to-partner and partner-to-SERPINB5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB5→partner) and Y-score (partner→SERPINB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Epidermis development →	+0.139	+2.603	<.001	<.001	3	11
STOMACH	Desmosome organization →	+0.534	+4.000	.001	<.001	3	10
LUNG_NSCLC_LUSC	Bundle of His cell to Purkinje myocyte communication →	+0.296	+3.858	<.001	.001	3	10
STOMACH	Nail development →	+0.481	+3.594	.007	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Homophilic cell-cell adhesion →	+0.138	+1.294	<.001	.002	3	10
BREAST	Hemidesmosome assembly →	+0.285	+3.051	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,544 associations by consensus.

Exploration

SERPINB5 survival (RNA) · tumor vs normal (RNA) · all SERPINB5 data types