Across TCGA patient cohorts, SERPINB4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,517 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SERPINB4-associated proteins across cancer lineages are S100A8, S100A12, and S100A9. Each is linked with SERPINB4 in more than 5 cancer types. Because this analysis shows association rather than direction, both SERPINB4-to-partner and partner-to-SERPINB4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB4→partner) and Y-score (partner→SERPINB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	S100A8 →	+1.524	+0.904	<.001	<.001	3	6
LUAD	S100A12 →	+1.250	+1.527	<.001	.001	3	5
LSCC	S100A9 →	+1.406	+2.458	<.001	<.001	3	5
PDAC	S100A9_T113 →	+1.247	+1.857	<.001	<.001	3	5
LSCC	SERPINB3 →	+2.332	+2.915	<.001	<.001	3	5
LUAD	MMP9 →	+0.936	+1.428	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,517 associations by consensus.

Exploration

SERPINB4 survival (RNA) · tumor vs normal (RNA) · all SERPINB4 data types