Across TCGA patient cohorts, SERPINB2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,461 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SERPINB2-associated genes across cancer lineages are SCEL, IL1RN, and SERPINB7. Each is linked with SERPINB2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SERPINB2-to-partner and partner-to-SERPINB2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB2→partner) and Y-score (partner→SERPINB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SCEL →	+2.125	+1.085	<.001	.002	3	5
UCEC	IL1RN →	+1.767	+1.212	<.001	.003	3	5
HNSC	SERPINB7 →	+2.031	+1.272	<.001	<.001	3	5
UCEC	SERPINB8 →	+0.886	+1.399	<.001	<.001	3	5
HNSC	MANBA →	-0.465	-1.179	<.001	<.001	3	4
UCEC	IVL →	+2.595	+1.184	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,461 associations by consensus.

Exploration

SERPINB2 survival (RNA) · tumor vs normal (RNA) · all SERPINB2 data types