Across TCGA cell cohorts, SERPINB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,613 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SERPINB2-associated GO terms across cancer lineages are Regulation of protein localization to mitochondrion, Cell-substrate junction organization, and Regulation of hemostasis. Each is linked with SERPINB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SERPINB2-to-partner and partner-to-SERPINB2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB2→partner) and Y-score (partner→SERPINB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of protein localization to mitochondrion →	+0.136	+3.831	<.001	.004	3	10
BREAST	Cell-substrate junction organization →	+0.164	+2.403	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of hemostasis →	+0.217	+4.058	<.001	.002	2	10
LUNG_NSCLC_LUSC	Cytoplasmic pattern recognition receptor signaling pathway →	+0.075	+3.033	.002	.006	3	9
LUNG_NSCLC_LUSC	Regulation of blood coagulation →	+0.216	+4.058	<.001	.002	2	10
OESOPHAGUS	Positive regulation of calcium ion transport into cytosol →	+0.269	+2.478	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,613 associations by consensus.

Exploration

SERPINB2 survival (RNA) · tumor vs normal (RNA) · all SERPINB2 data types