Across TCGA cell cohorts, SERPINB2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SERPINB2-associated genes across cancer lineages are HEMGN, OR52B2, and REG1B. Each is linked with SERPINB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINB2-to-partner and partner-to-SERPINB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB2→partner) and Y-score (partner→SERPINB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	HEMGN →	+0.009	+2.921	.002	.005	3	1
SKIN	OR52B2 →	+0.022	+3.084	<.001	.002	3	1
LARGE_INTESTINE	REG1B →	+3.348	+3.196	<.001	.007	3	1
LARGE_INTESTINE	MXRA5 →	+1.252	+3.482	<.001	.008	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

SERPINB2 survival (RNA) · tumor vs normal (RNA) · all SERPINB2 data types