SERPINB12

Across TCGA patient cohorts, SERPINB12 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,717 significant associations in total. THYM shows the largest number of these associations.

The most reproducible SERPINB12-associated GO terms across cancer lineages are Regulation of translation in response to stress, Regulation of protein ubiquitination, and Molting cycle. Each is linked with SERPINB12 in more than 12 cancer types. Because this analysis shows association rather than direction, both SERPINB12-to-partner and partner-to-SERPINB12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translation in response to stress grouped by SERPINB12-low versus SERPINB12-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB12→partner) and Y-score (partner→SERPINB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Regulation of translation in response to stress →	+0.064	+1.509	<.001	<.001	3	13
KIRC	Regulation of protein ubiquitination →	+0.029	+0.027	<.001	<.001	3	12
ESCA	Molting cycle →	+0.057	+0.721	<.001	<.001	3	12
THYM	Regulation of post-translational protein modification →	+0.037	+1.619	<.001	<.001	3	12
ESCA	Skin epidermis development →	+0.061	+0.899	<.001	<.001	3	11
UCS	Positive regulation of canonical Wnt signaling pathway →	+0.041	+0.555	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,717 associations by consensus.

Regulation of translation in response to stress by SERPINB12 expression — THYM

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