SERPINB12

Across TCGA patient cohorts, SERPINB12 protein abundance is significantly associated with the RNA expression of many other genes, with 1,611 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SERPINB12-associated genes across cancer lineages are SPRR4, TGM5, and CHKA. Each is linked with SERPINB12 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINB12-to-partner and partner-to-SERPINB12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINB12 versus SPRR4 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB12→partner) and Y-score (partner→SERPINB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SPRR4 →	+2.021	+1.225	<.001	<.001	3	2
HNSC	TGM5 →	+1.006	+0.807	<.001	.001	3	2
HNSC	CHKA →	-0.509	-0.804	.003	.002	3	2
LSCC	TACR1 →	-0.668	-0.810	<.001	.003	3	2
LSCC	CSTA →	+1.450	+1.364	.001	<.001	3	2
HNSC	FAM83C →	+1.381	+0.927	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,611 associations by consensus.

SERPINB12 vs SPRR4 — HNSC

Explore this scatter interactively →