SERPINB12

Across TCGA cell cohorts, SERPINB12 RNA expression is significantly associated with the go_rna of many other GO terms, with 768 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SERPINB12-associated GO terms across cancer lineages are Regulation of protein binding, Regulation of action potential, and Regulation of cardiac muscle cell action potential. Each is linked with SERPINB12 in more than 3 cancer types. Because this analysis shows association rather than direction, both SERPINB12-to-partner and partner-to-SERPINB12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein binding grouped by SERPINB12-low versus SERPINB12-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB12→partner) and Y-score (partner→SERPINB12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of protein binding →	+0.058	+0.028	.004	.005	3	4
SKIN	Regulation of action potential →	+0.097	+0.024	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of cardiac muscle cell action potential →	+0.106	+0.128	.001	.004	3	3
BREAST	Positive regulation of oxidoreductase activity →	-0.246	-0.033	.002	.009	3	3
BREAST	Biological process involved in interaction with host →	+0.075	+0.039	<.001	.006	3	3
BREAST	Adenylate cyclase-activating dopamine receptor signaling pathway →	-0.152	-0.030	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 768 associations by consensus.

Regulation of protein binding by SERPINB12 expression — BREAST

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