SERPINB10

Across TCGA cell cohorts, SERPINB10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,775 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SERPINB10-associated GO terms across cancer lineages are Regulation of smooth muscle contraction, Regulation of cytokine-mediated signaling pathway, and Negative regulation of immune response. Each is linked with SERPINB10 in more than 6 cancer types. Because this analysis shows association rather than direction, both SERPINB10-to-partner and partner-to-SERPINB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of smooth muscle contraction grouped by SERPINB10-low versus SERPINB10-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB10→partner) and Y-score (partner→SERPINB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of smooth muscle contraction →	+0.084	+0.282	<.001	.001	3	6
BLOOD_Lymphoma	Regulation of cytokine-mediated signaling pathway →	+0.045	+0.777	<.001	.009	3	6
BLOOD_Leukemia	Negative regulation of immune response →	+0.054	+1.706	.001	.006	3	6
BLOOD_Leukemia	Positive regulation of cytokine-mediated signaling pathway →	+0.066	+1.686	<.001	.001	3	6
BREAST	Regulation of positive chemotaxis →	+0.177	+0.184	<.001	.001	3	6
SKIN	Positive regulation of response to cytokine stimulus →	+0.060	+0.435	.003	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,775 associations by consensus.

Regulation of smooth muscle contraction by SERPINB10 expression — CNS

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