SERPINB10

Across TCGA cell cohorts, SERPINB10 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SERPINB10-associated genes across cancer lineages are MTRNR2L10, OPN1MW3, and HES3. Each is linked with SERPINB10 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINB10-to-partner and partner-to-SERPINB10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTRNR2L10 grouped by SERPINB10-low versus SERPINB10-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB10→partner) and Y-score (partner→SERPINB10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MTRNR2L10 →	+0.013	+5.000	<.001	.006	3	1
PANCREAS	OPN1MW3 →	+0.013	+5.614	<.001	.002	3	1
STOMACH	HES3 →	+0.166	+5.285	<.001	.003	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	IQCF3 →	+0.049	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP19-3 →	+0.132	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MTRNR2L10 by SERPINB10 expression — PANCREAS

Explore this box plot interactively →