SERPINB1

Across TCGA patient cohorts, SERPINB1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,346 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SERPINB1-associated genes across cancer lineages are SQOR, SERPINB6, and CARD6. Each is linked with SERPINB1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SERPINB1-to-partner and partner-to-SERPINB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINB1 versus SQOR in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB1→partner) and Y-score (partner→SERPINB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SQOR →	+1.139	+0.458	<.001	<.001	3	8
COAD	SERPINB6 →	+0.786	+0.477	<.001	<.001	3	7
GBM	CARD6 →	+0.886	+0.707	<.001	<.001	3	7
UCEC	CAST →	+0.631	+0.538	<.001	<.001	3	7
OV	CASP4 →	+0.825	+0.467	<.001	.002	3	7
HNSC	ZNF286B →	-0.698	-0.709	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,346 associations by consensus.

SERPINB1 vs SQOR — UCEC

Explore this scatter interactively →