SERPINA7

Across TCGA patient cohorts, SERPINA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,040 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible SERPINA7-associated GO terms across cancer lineages are Regulation of very-low-density lipoprotein particle remodeling, Regulation of intestinal absorption, and Nucleoside bisphosphate metabolic process. Each is linked with SERPINA7 in more than 10 cancer types. Because this analysis shows association rather than direction, both SERPINA7-to-partner and partner-to-SERPINA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of very-low-density lipoprotein particle remodeling grouped by SERPINA7-low versus SERPINA7-high in CESC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA7→partner) and Y-score (partner→SERPINA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	Regulation of very-low-density lipoprotein particle remodeling →	+0.603	+0.089	<.001	.001	3	11
CHOL	Regulation of intestinal absorption →	+0.189	+3.158	<.001	<.001	3	8
ESCA	Nucleoside bisphosphate metabolic process →	+0.039	+0.231	<.001	.002	2	9
CHOL	Thioester metabolic process →	+0.055	+3.638	.001	<.001	3	8
CHOL	Putrescine biosynthetic process →	+0.071	+2.405	<.001	<.001	3	8
CHOL	Isoprenoid transport →	+0.174	+2.902	<.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,040 associations by consensus.

Regulation of very-low-density lipoprotein particle remodeling by SERPINA7 expression — CESC

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