SERPINA7

Across TCGA cell cohorts, SERPINA7 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SERPINA7-associated genes across cancer lineages are CRYAA, GPR101, and OR1G1. Each is linked with SERPINA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINA7-to-partner and partner-to-SERPINA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYAA grouped by SERPINA7-low versus SERPINA7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA7→partner) and Y-score (partner→SERPINA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CRYAA →	+0.057	+4.705	.001	.003	3	1
BLOOD_Leukemia	GPR101 →	+0.146	+4.551	<.001	.004	3	1
BLOOD_Leukemia	OR1G1 →	+0.044	+4.705	.002	.003	3	1
BLOOD_Leukemia	OR10T2 →	+0.863	+4.276	<.001	.007	3	1
BLOOD_Leukemia	KRTAP21-2 →	+0.062	+4.539	.001	.007	3	1
BLOOD_Leukemia	FAM24A →	+0.061	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

CRYAA by SERPINA7 expression — BLOOD_Leukemia

Explore this box plot interactively →