SERPINA6

Across TCGA patient cohorts, SERPINA6 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,970 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERPINA6-associated proteins across cancer lineages are SERPINA7, SERPIND1, and SERPINF1. Each is linked with SERPINA6 in more than 9 cancer types. Because this analysis shows association rather than direction, both SERPINA6-to-partner and partner-to-SERPINA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINA6 versus SERPINA7 in GBM, with a Pearson correlation of 0.91.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA6→partner) and Y-score (partner→SERPINA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SERPINA7 →	+1.000	+1.008	<.001	<.001	3	10
COAD	SERPIND1 →	+1.006	+0.745	<.001	<.001	3	10
CCRCC	SERPINF1 →	+0.946	+0.789	<.001	<.001	3	10
CCRCC	SERPINF2 →	+0.890	+0.909	<.001	<.001	3	10
GBM	SERPING1 →	+0.926	+0.973	<.001	<.001	3	10
GBM	SHBG →	+1.013	+0.814	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,970 associations by consensus.

SERPINA6 vs SERPINA7 — GBM

Explore this scatter interactively →