SERPINA6

Across TCGA cell cohorts, SERPINA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,794 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SERPINA6-associated GO terms across cancer lineages are Positive regulation of blood pressure by epinephrine-norepinephrine, Left ventricular cardiac muscle tissue morphogenesis, and Response to hyperoxia. Each is linked with SERPINA6 in more than 5 cancer types. Because this analysis shows association rather than direction, both SERPINA6-to-partner and partner-to-SERPINA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of blood pressure by epinephrine-norepinephrine grouped by SERPINA6-low versus SERPINA6-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA6→partner) and Y-score (partner→SERPINA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.162	+0.139	.001	.005	3	6
SOFT_TISSUE	Left ventricular cardiac muscle tissue morphogenesis →	-0.170	-0.122	.002	.001	3	5
SOFT_TISSUE	Response to hyperoxia →	+0.078	+0.089	.002	.001	3	5
BONE	Protein oxidation →	+1.342	+0.196	<.001	.003	3	5
BONE	Positive regulation of vasculature development →	+0.083	+0.201	.003	.004	3	5
LIVER	Glucocorticoid biosynthetic process →	+1.838	+3.555	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,794 associations by consensus.

Positive regulation of blood pressure by epinephrine-norepinephrine by SERPINA6 expression — SOFT_TISSUE

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