SERPINA2

Across TCGA patient cohorts, SERPINA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,068 significant associations in total. THCA shows the largest number of these associations.

The most reproducible SERPINA2-associated GO terms across cancer lineages are Nucleobase-containing small molecule interconversion, Regulation of nitric oxide metabolic process, and Positive regulation of myeloid leukocyte differentiation. Each is linked with SERPINA2 in more than 8 cancer types. Because this analysis shows association rather than direction, both SERPINA2-to-partner and partner-to-SERPINA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleobase-containing small molecule interconversion grouped by SERPINA2-low versus SERPINA2-high in CHOL.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA2→partner) and Y-score (partner→SERPINA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	Nucleobase-containing small molecule interconversion →	+0.049	+0.068	.004	.009	1	9
LAML	Regulation of nitric oxide metabolic process →	+0.061	+0.086	<.001	.001	3	6
ESCA	Positive regulation of myeloid leukocyte differentiation →	+0.048	+0.058	<.001	<.001	3	6
LAML	Leukocyte chemotaxis →	+0.042	+0.062	<.001	<.001	3	6
LAML	Heterotypic cell-cell adhesion →	+0.060	+0.071	<.001	<.001	3	6
ESCA	Modified amino acid transport →	+0.025	+0.094	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,068 associations by consensus.

Nucleobase-containing small molecule interconversion by SERPINA2 expression — CHOL

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