Across TCGA pan-cancer cohorts, SERPINA13P Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SERPINA13P data layer compared with 14 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher SERPINA13P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SERPINA13P expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

LUSC and SKCM are the cancer types where SERPINA13P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.213	0.764	<.001	40	view →
SKCM	DFS	Median	II,III,IV	0.533	0.202	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SERPINA13P tumor-vs-normal RNA expression · all SERPINA13P data types