SERPINA13P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SERPINA13P mutation is significantly associated with the RNA expression of many other genes, with 2,315 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINA13P-associated genes across cancer lineages are MMS19, KMT2D, and SRRM2. Each is linked with SERPINA13P in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINA13P-to-partner and partner-to-SERPINA13P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA13P→partner) and Y-score (partner→SERPINA13P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMMS19 →+0.465+2.617.002.00532
UCECKMT2D →+0.663+3.659<.001.00132
UCECSRRM2 →+0.565+3.332<.001.00532
UCECSPNS1 →+0.374+3.343.006.00532
UCECKCTD13 →+0.389+3.491.006.00232
UCECMAMDC4 →+0.665+2.600.002.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,315 associations by consensus.

Exploration