SERPINA12

Across TCGA cell cohorts, SERPINA12 RNA expression is significantly associated with the go_rna of many other GO terms, with 213 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SERPINA12-associated GO terms across cancer lineages are Toxin catabolic process, Cell fate commitment involved in formation of primary germ layer, and Promoter clearance during DNA-templated transcription. Each is linked with SERPINA12 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINA12-to-partner and partner-to-SERPINA12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Toxin catabolic process grouped by SERPINA12-low versus SERPINA12-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA12→partner) and Y-score (partner→SERPINA12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Toxin catabolic process →	-0.109	-0.031	.005	.004	3	3
BREAST	Cell fate commitment involved in formation of primary germ layer →	-0.106	-0.031	.008	.006	3	2
BREAST	Promoter clearance during DNA-templated transcription →	+0.079	+0.057	.008	.004	3	2
BREAST	RNA polymerase II promoter clearance →	+0.079	+0.057	.008	.004	3	2
BREAST	Negative regulation of transcription by RNA polymerase III →	+0.126	+0.031	<.001	.005	3	2
BREAST	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.060	+0.044	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 213 associations by consensus.

Toxin catabolic process by SERPINA12 expression — BREAST

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