SERPINA11

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SERPINA11 RNA expression is significantly associated with the go_rna of many other GO terms, with 938 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SERPINA11-associated GO terms across cancer lineages are Positive regulation of translation, Regulation of membrane hyperpolarization, and Regulation of protein maturation. Each is linked with SERPINA11 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINA11-to-partner and partner-to-SERPINA11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA11→partner) and Y-score (partner→SERPINA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPositive regulation of translation →+0.046+0.014.001.00733
BREASTRegulation of membrane hyperpolarization →-0.122-0.282<.001.00133
BREASTRegulation of protein maturation →-0.090-0.293.004.00733
BREASTPyramidal neuron development →+0.127+0.217<.001.00733
BREASTDermatan sulfate proteoglycan biosynthetic process →-0.084-0.344<.001<.00133
BREASTCardiac muscle cell fate commitment →-0.903-0.312<.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 938 associations by consensus.

Exploration