SERPINA10

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SERPINA10 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,380 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERPINA10-associated proteins across cancer lineages are PPP4R4_S775, RMDN2, and CACNA2D2. Each is linked with SERPINA10 in more than 5 cancer types. Because this analysis shows association rather than direction, both SERPINA10-to-partner and partner-to-SERPINA10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINA10 versus PPP4R4_S775 in LSCC, with a Pearson correlation of 0.88.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA10→partner) and Y-score (partner→SERPINA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCPPP4R4_S775 →+2.197+1.062<.001<.00136
GBMRMDN2 →+0.393+0.340<.001<.00134
LUADCACNA2D2 →+0.637+0.484<.001<.00134
BRCACDK18_S14 →+0.898+0.556<.001<.00134
GBMTPPP3 →+0.960+0.308<.001.00334
LSCCQDPR →+0.274+0.629<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,380 associations by consensus.

SERPINA10 vs PPP4R4_S775 — LSCC

Per-sample scatter of SERPINA10 vs PPP4R4_S775 in LSCC (Pearson r = 0.88).

Explore this scatter interactively →

Exploration