SERPINA10

Across TCGA patient cohorts, SERPINA10 mutation is significantly associated with the RNA expression of many other genes, with 2,603 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SERPINA10-associated genes across cancer lineages are LINC01784, HMGN2P26, and SERAC1. Each is linked with SERPINA10 in more than 3 cancer types. Because this analysis shows association rather than direction, both SERPINA10-to-partner and partner-to-SERPINA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01784 grouped by SERPINA10-low versus SERPINA10-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA10→partner) and Y-score (partner→SERPINA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	LINC01784 →	+0.104	+7.939	<.001	.008	3	4
LUSC	HMGN2P26 →	+0.174	+3.906	<.001	.009	3	4
SKCM	SERAC1 →	+0.333	+1.097	<.001	.004	3	3
LUAD	RNASEH1P2 →	+0.106	+4.279	.001	<.001	3	3
SKCM	GLRX2 →	+0.407	+1.469	<.001	<.001	3	3
SKCM	UFD1 →	+0.204	+1.912	.006	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,603 associations by consensus.

LINC01784 by SERPINA10 expression — PRAD

Explore this box plot interactively →