Across TCGA patient cohorts, SERPINA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,869 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERPINA1-associated proteins across cancer lineages are SSRP1, ARHGAP18, and TLR2. Each is linked with SERPINA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SERPINA1-to-partner and partner-to-SERPINA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA1→partner) and Y-score (partner→SERPINA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SSRP1 →	-0.429	-1.516	<.001	<.001	3	6
GBM	ARHGAP18 →	+0.443	+1.259	<.001	<.001	3	6
GBM	TLR2 →	+0.654	+1.575	<.001	<.001	3	5
LSCC	PUS7 →	-0.682	-1.944	<.001	<.001	3	5
GBM	SMARCE1 →	-0.310	-1.254	<.001	<.001	3	5
OV	XPO5 →	-0.574	-1.335	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,869 associations by consensus.

Exploration

SERPINA1 survival (RNA) · tumor vs normal (RNA) · all SERPINA1 data types