SERP2

Across TCGA cell cohorts, SERP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,214 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SERP2-associated GO terms across cancer lineages are Purine ribonucleotide biosynthetic process, ATP biosynthetic process, and Proton motive force-driven ATP synthesis. Each is linked with SERP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SERP2-to-partner and partner-to-SERP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleotide biosynthetic process grouped by SERP2-low versus SERP2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERP2→partner) and Y-score (partner→SERP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Purine ribonucleotide biosynthetic process →	+0.075	+1.152	<.001	.002	3	8
OVARY	ATP biosynthetic process →	+0.101	+1.345	<.001	.001	3	8
OVARY	Proton motive force-driven ATP synthesis →	+0.098	+1.186	.001	.008	3	8
OVARY	Regulation of myoblast fusion →	+0.063	+0.903	.001	.001	3	8
OVARY	Respiratory electron transport chain →	+0.081	+1.037	.001	.007	3	8
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.063	+0.887	.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,214 associations by consensus.

Purine ribonucleotide biosynthetic process by SERP2 expression — OVARY

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