SERP1

Across TCGA patient cohorts, SERP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,524 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERP1-associated proteins across cancer lineages are GOLGB1, DLG1, and EIF2A. Each is linked with SERP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both SERP1-to-partner and partner-to-SERP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERP1 versus GOLGB1 in BRCA, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERP1→partner) and Y-score (partner→SERP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GOLGB1 →	+0.280	+0.367	<.001	<.001	3	5
OV	DLG1 →	+0.372	+0.657	<.001	<.001	3	4
LSCC	EIF2A →	+0.406	+0.597	<.001	<.001	3	4
LSCC	GMPS →	+0.596	+0.555	<.001	<.001	3	4
LSCC	DCUN1D1 →	+0.374	+0.562	<.001	<.001	3	4
CCRCC	SLC33A1 →	+0.373	+0.302	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,524 associations by consensus.

SERP1 vs GOLGB1 — BRCA

Explore this scatter interactively →