SERINC5

Across TCGA patient cohorts, SERINC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,493 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERINC5-associated proteins across cancer lineages are TRIM2, SULT2B1, and EPB41L1. Each is linked with SERINC5 in more than 5 cancer types. Because this analysis shows association rather than direction, both SERINC5-to-partner and partner-to-SERINC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERINC5 versus TRIM2 in HNSC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERINC5→partner) and Y-score (partner→SERINC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRIM2 →	+0.650	+0.549	<.001	<.001	3	6
CCRCC	SULT2B1 →	+1.062	+0.526	<.001	<.001	3	5
HNSC	EPB41L1 →	+0.755	+0.654	<.001	<.001	3	5
UCEC	EPHX1 →	+0.599	+0.573	.001	.002	3	5
PDAC	ZNF687_S1191 →	+0.457	+0.419	<.001	<.001	3	4
GBM	UNC13D →	-0.425	-0.671	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,493 associations by consensus.

SERINC5 vs TRIM2 — HNSC

Explore this scatter interactively →