Across TCGA patient cohorts, SERINC4 RNA expression is significantly associated with the RNA expression of many other genes, with 4,239 significant associations in total. SARC shows the largest number of these associations.

The most reproducible SERINC4-associated genes across cancer lineages are HMGN2P41, FANCL, and RBBP6. Each is linked with SERINC4 in more than 10 cancer types. Because this analysis shows association rather than direction, both SERINC4-to-partner and partner-to-SERINC4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERINC4→partner) and Y-score (partner→SERINC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HMGN2P41 →	+1.458	+0.005	<.001	<.001	3	10
UCEC	FANCL →	+0.642	+0.004	<.001	<.001	3	10
READ	RBBP6 →	+0.560	+0.006	.002	.001	3	10
READ	CTDSPL2 →	+0.612	+0.008	<.001	.002	3	10
READ	ZCRB1 →	+0.655	+0.006	<.001	.001	3	10
UCEC	YY1AP1 →	+0.540	+0.003	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,239 associations by consensus.

Exploration

SERINC4 survival (RNA) · tumor vs normal (RNA) · all SERINC4 data types