Across TCGA patient cohorts, SERINC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,309 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SERINC4-associated GO terms across cancer lineages are tRNA methylation, DNA double-strand break processing, and Constitutive heterochromatin formation. Each is linked with SERINC4 in more than 7 cancer types. Because this analysis shows association rather than direction, both SERINC4-to-partner and partner-to-SERINC4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERINC4→partner) and Y-score (partner→SERINC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	tRNA methylation →	+0.026	+0.006	.002	<.001	2	8
SARC	DNA double-strand break processing →	+0.036	+0.007	<.001	<.001	3	6
SARC	Constitutive heterochromatin formation →	+0.031	+0.008	.002	.001	3	6
KIRP	Double-strand break repair via single-strand annealing →	+0.023	+0.003	.001	<.001	3	5
SARC	Obsolete regulation of histone acetylation →	+0.032	+0.009	<.001	<.001	3	5
SARC	Homologous recombination →	+0.020	+0.011	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,309 associations by consensus.

Exploration

SERINC4 survival (RNA) · tumor vs normal (RNA) · all SERINC4 data types