SERINC3

Across TCGA patient cohorts, SERINC3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,761 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERINC3-associated genes across cancer lineages are RAB22A, TUBA4A, and PRNP. Each is linked with SERINC3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SERINC3-to-partner and partner-to-SERINC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERINC3 versus RAB22A in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERINC3→partner) and Y-score (partner→SERINC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAB22A →	+0.560	+0.222	<.001	<.001	3	4
HNSC	TUBA4A →	+1.429	+0.201	<.001	.002	3	3
HNSC	PRNP →	+0.816	+0.181	.001	.001	3	3
HNSC	GPR157 →	+0.850	+0.249	.009	.003	3	3
CCRCC	RPS16P5 →	-0.489	-0.381	.007	.002	3	3
OV	ARHGAP4 →	-0.838	-0.418	.006	.005	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,761 associations by consensus.

SERINC3 vs RAB22A — HNSC

Explore this scatter interactively →