SERINC3

Across TCGA cell cohorts, SERINC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,601 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SERINC3-associated GO terms across cancer lineages are Viral process, Endoplasmic reticulum to cytosol transport, and Viral life cycle. Each is linked with SERINC3 in more than 16 cancer types. Because this analysis shows association rather than direction, both SERINC3-to-partner and partner-to-SERINC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by SERINC3-low versus SERINC3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERINC3→partner) and Y-score (partner→SERINC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Viral process →	+0.116	+1.532	<.001	<.001	3	17
BONE	Endoplasmic reticulum to cytosol transport →	+0.162	+1.415	<.001	<.001	3	16
BONE	Viral life cycle →	+0.115	+1.587	<.001	<.001	3	16
BLOOD_Myeloma	Endoplasmic reticulum unfolded protein response →	+0.116	+0.880	.002	.005	3	16
BONE	Retrograde protein transport, ER to cytosol →	+0.162	+1.415	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Membrane protein proteolysis →	+0.115	+0.867	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,601 associations by consensus.

Viral process by SERINC3 expression — BONE

Explore this box plot interactively →