SERINC2

Across TCGA patient cohorts, SERINC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,343 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERINC2-associated proteins across cancer lineages are GALE, RPS6KA1, and SLC9A1. Each is linked with SERINC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SERINC2-to-partner and partner-to-SERINC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERINC2 versus GALE in BRCA, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERINC2→partner) and Y-score (partner→SERINC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GALE →	+0.504	+0.827	<.001	<.001	3	7
UCEC	RPS6KA1 →	+0.311	+1.279	<.001	<.001	3	6
BRCA	SLC9A1 →	+0.363	+1.080	.001	<.001	3	5
PDAC	KIAA1522 →	+0.312	+0.651	.004	.003	3	5
BRCA	LYPLA2 →	+0.323	+0.842	<.001	<.001	3	5
HNSC	TXNDC17 →	+0.371	+0.967	.005	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,343 associations by consensus.

SERINC2 vs GALE — BRCA

Explore this scatter interactively →