SERINC2

Across TCGA patient cohorts, SERINC2 protein abundance is significantly associated with the RNA expression of many other genes, with 82 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SERINC2-associated genes across cancer lineages are AVPI1, PRELID3A, and TMPRSS2. Each is linked with SERINC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERINC2-to-partner and partner-to-SERINC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERINC2 versus AVPI1 in OV, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERINC2→partner) and Y-score (partner→SERINC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AVPI1 →	-0.597	-0.903	.007	.009	3	1
HNSC	PRELID3A →	-1.008	-0.429	.005	.001	2	2
OV	TMPRSS2 →	+0.882	+1.020	.005	.002	3	1
OV	LINC00381 →	+0.131	+1.206	.002	.009	3	1
OV	HNRNPA1P36 →	-0.347	-0.960	.002	.005	3	1
OV	SNHG7 →	-1.313	-0.920	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 82 associations by consensus.

SERINC2 vs AVPI1 — OV

Explore this scatter interactively →