SERINC1

Across TCGA cell cohorts, SERINC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,478 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SERINC1-associated GO terms across cancer lineages are Golgi vesicle transport, 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process, and Endoplasmic reticulum mannose trimming. Each is linked with SERINC1 in more than 17 cancer types. Because this analysis shows association rather than direction, both SERINC1-to-partner and partner-to-SERINC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by SERINC1-low versus SERINC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERINC1→partner) and Y-score (partner→SERINC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Golgi vesicle transport →	+0.054	+0.787	.003	.002	3	18
STOMACH	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.128	+0.860	<.001	.004	3	16
BREAST	Endoplasmic reticulum mannose trimming →	+0.104	+0.561	.002	.009	3	16
BONE	Protein demannosylation →	+0.097	+0.725	.001	<.001	3	16
BONE	Protein alpha-1,2-demannosylation →	+0.097	+0.725	.001	<.001	3	16
STOMACH	Process utilizing autophagic mechanism →	+0.057	+0.696	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,478 associations by consensus.

Golgi vesicle transport by SERINC1 expression — BONE

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