SERHL2

Across TCGA patient cohorts, SERHL2 protein abundance is significantly associated with the RNA expression of many other genes, with 123 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SERHL2-associated genes across cancer lineages are RND2, SC5D, and PRPF3. Each is linked with SERHL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERHL2-to-partner and partner-to-SERHL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERHL2 versus RND2 in BRCA, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERHL2→partner) and Y-score (partner→SERHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RND2 →	-1.631	-0.986	.005	.005	3	1
BRCA	SC5D →	+1.882	+1.204	.006	.007	3	1
BRCA	PRPF3 →	-0.713	-0.934	.006	.008	3	1
BRCA	POF1B →	+2.193	+0.966	.001	.005	3	1
BRCA	STEAP4 →	+1.783	+0.833	<.001	.001	3	1
BRCA	ALDH3B2 →	+2.589	+1.070	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 123 associations by consensus.

SERHL2 vs RND2 — BRCA

Explore this scatter interactively →