SERHL2

Across TCGA cell cohorts, SERHL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,152 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SERHL2-associated GO terms across cancer lineages are Purine nucleoside triphosphate biosynthetic process, Ribonucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with SERHL2 in more than 11 cancer types. Because this analysis shows association rather than direction, both SERHL2-to-partner and partner-to-SERHL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine nucleoside triphosphate biosynthetic process grouped by SERHL2-low versus SERHL2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERHL2→partner) and Y-score (partner→SERHL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Purine nucleoside triphosphate biosynthetic process →	+0.116	+0.866	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Ribonucleoside triphosphate biosynthetic process →	+0.108	+0.927	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Purine ribonucleoside triphosphate biosynthetic process →	+0.116	+0.866	<.001	.001	3	11
OESOPHAGUS	ATP synthesis coupled electron transport →	+0.130	+0.926	.008	.007	2	12
OESOPHAGUS	Mitochondrial ATP synthesis coupled electron transport →	+0.130	+0.926	.008	.007	2	12
OVARY	Proton motive force-driven mitochondrial ATP synthesis →	+0.116	+0.722	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,152 associations by consensus.

Purine nucleoside triphosphate biosynthetic process by SERHL2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →