SERHL

Across TCGA patient cohorts, SERHL RNA expression is significantly associated with the mutation status of many other genes, with 7,758 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERHL-associated genes across cancer lineages are TP53, TTN, and CIT. Each is linked with SERHL in more than 4 cancer types. Because this analysis shows association rather than direction, both SERHL-to-partner and partner-to-SERHL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by SERHL-low versus SERHL-high in LIHC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERHL→partner) and Y-score (partner→SERHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TP53 →	+0.988	+0.132	.007	.006	2	5
UCEC	TTN →	+0.692	+0.294	<.001	<.001	3	4
UCEC	CIT →	+2.007	+0.560	<.001	<.001	3	4
UCEC	ANK3 →	+1.674	+0.321	<.001	<.001	3	4
UCEC	NAV2 →	+1.228	+0.321	<.001	<.001	3	4
UCEC	DSCAML1 →	+1.989	+0.355	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,758 associations by consensus.

TP53 by SERHL expression — LIHC

Explore this box plot interactively →