SERF2

Across TCGA patient cohorts, SERF2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERF2-associated genes across cancer lineages are Platelets, CD4+ Tem, and NK cells. Each is linked with SERF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERF2-to-partner and partner-to-SERF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by SERF2-low versus SERF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERF2→partner) and Y-score (partner→SERF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Platelets →	+0.034	+2.733	.002	.045	3	2
UCEC	CD4+ Tem →	+0.032	+3.496	<.001	.027	3	1
ESCA	NK cells →	+0.006	+5.709	<.001	.037	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Platelets by SERF2 expression — UCEC

Explore this box plot interactively →