Across TCGA pan-cancer cohorts, SERF1B RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SERF1B data layer.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SERF1B RNA is associated with better overall survival. In most high-consensus cancer types, elevated SERF1B expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCS show a favorable association.
LUAD, UCS, and KIRC are the cancer types where SERF1B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.