SERBP1P6

Across TCGA pan-cancer cohorts, SERBP1P6 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated SERBP1P6 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher SERBP1P6 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SERBP1P6 expression acts as an unfavorable survival marker, although some lineages such as CESC and KIRC show a favorable association.

LGG, HNSC, and CESC are the cancer types where SERBP1P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Tertile	All	0.624	0.807	<.001	46	view →
HNSC	OS	Tertile	All	0.581	0.804	.006	28	view →
CESC	OS	Quartile	All	0.945	0.820	.009	24	view →
KIRC	DFS	Quartile	IV	0.623	0.222	.006	21	view →
COAD	OS	Median	IV	0.270	0.842	.007	19	view →
CHOL	DFS	Tertile	All	0.229	0.613	<.001	18	view →
SARC	DFS	Quartile	All	0.213	0.513	.001	17	view →
UVM	OS	Median	III,IV	0.240	0.836	.001	16	view →
LIHC	OS	Median	III,IV	0.882	0.522	.001	16	view →
PRAD	DFS	Quartile	All	0.955	0.729	<.001	16	view →
LUAD	DFS	Median	All	0.760	0.818	.038	14	view →
LUSC	OS	Quartile	II,III,IV	0.709	0.494	.012	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

SERBP1P6–LGG (DFS)

Open the LGG breakdown →