SERBP1P5

Across TCGA pan-cancer cohorts, SERBP1P5 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of SERBP1P5’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SERBP1P5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SERBP1P5 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

COAD, LUSC, and KICH are the cancer types where SERBP1P5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SERBP1P5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	+0.834	<.001	10	view →
LUSC	Male	III,IV	+0.737	<.001	7	view →
KICH	Female	II,III,IV	−0.348	<.001	6	view →
HNSC	Male	All	+0.341	<.001	5	view →
LUAD	All	All	+0.357	<.001	4	view →
BLCA	Male	III,IV	+0.354	.035	2	view →
UCEC	All	All	+0.353	.042	2	view →
CHOL	All	All	+0.288	.007	2	view →
PRAD	All	All	+0.239	.003	2	view →
THCA	All	All	−0.173	.001	2	view →
LIHC	All	All	+0.131	.002	2	view →
STAD	All	II,III,IV	+0.348	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

SERBP1P5–COAD

Open the COAD breakdown →