SERBP1P4

Across TCGA pan-cancer cohorts, SERBP1P4 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated SERBP1P4 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SERBP1P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SERBP1P4 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

KIRP, READ, and KIRC are the cancer types where SERBP1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.469	0.867	<.001	138	view →
READ	OS	Tertile	All	0.198	0.822	<.001	108	view →
KIRC	OS	Tertile	II,III,IV	0.581	0.803	.001	90	view →
LUSC	DFS	Tertile	III,IV	0.117	0.784	<.001	69	view →
COAD	OS	Tertile	III,IV	0.520	0.783	<.001	66	view →
UCEC	OS	Tertile	All	0.714	0.885	<.001	66	view →
SKCM	DFS	Tertile	II,III,IV	0.521	0.707	.001	57	view →
LIHC	OS	Tertile	II,III,IV	0.092	0.696	<.001	45	view →
PAAD	OS	Tertile	II,III,IV	0.213	0.556	.014	36	view →
LUAD	DFS	Tertile	All	0.666	0.802	.002	36	view →
HNSC	DFS	Tertile	IV	0.412	0.656	.004	27	view →
STAD	OS	Tertile	IV	0.067	0.593	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

SERBP1P4–KIRP (DFS)

Open the KIRP breakdown →