SERBP1

Across TCGA pan-cancer cohorts, SERBP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated SERBP1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SERBP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SERBP1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, CCRCC, and LUAD are the cancer types where SERBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.882	.022	30	view →
CCRCC	OS	Tertile	III,IV	0.462	0.772	.007	21	view →
LUAD	DFS	Quartile	II,III,IV	0.991	0.658	.016	19	view →
GBM	DFS	Tertile	All	0.261	0.485	.014	4	view →
UCEC	DFS	Median	II,III,IV	0.882	0.533	.035	4	view →
PDAC	OS	Median	II,III,IV	0.277	0.501	.027	4	view →
HNSC	DFS	Median	All	0.719	0.558	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SERBP1–COAD (DFS)

Open the COAD breakdown →