SERBP1

Across TCGA cell cohorts, SERBP1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SERBP1-associated genes across cancer lineages are FCGR3B and BTNL2. Each is linked with SERBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERBP1-to-partner and partner-to-SERBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCGR3B grouped by SERBP1-low versus SERBP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERBP1→partner) and Y-score (partner→SERBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FCGR3B →	+0.174	+4.467	<.001	.004	3	1
LARGE_INTESTINE	BTNL2 →	+0.081	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FCGR3B by SERBP1 expression — LARGE_INTESTINE

Explore this box plot interactively →