Across TCGA patient cohorts, SEPTIN9 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,571 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEPTIN9-associated proteins across cancer lineages are WDR45B, SEC11C, and P2RY8_S324. Each is linked with SEPTIN9 in more than 3 cancer types. Because this analysis shows association rather than direction, both SEPTIN9-to-partner and partner-to-SEPTIN9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN9→partner) and Y-score (partner→SEPTIN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	WDR45B →	+0.338	+0.414	<.001	<.001	3	4
LSCC	SEC11C →	-0.768	-0.434	<.001	<.001	3	4
CCRCC	P2RY8_S324 →	-0.587	-0.374	.003	.004	3	3
PDAC	PAIP2B →	-0.636	-0.351	<.001	.001	3	3
COAD	RBM12B_S280 →	+0.526	+0.642	.004	.002	3	3
OV	RUNX1 →	+0.590	+0.868	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,571 associations by consensus.

Exploration

SEPTIN9 survival (RNA) · tumor vs normal (RNA) · all SEPTIN9 data types