Across TCGA patient cohorts, SEPTIN9 protein abundance is significantly associated with the RNA expression of many other genes, with 11,126 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SEPTIN9-associated genes across cancer lineages are CPED1, AHNAK, and SCN7A. Each is linked with SEPTIN9 in more than 3 cancer types. Because this analysis shows association rather than direction, both SEPTIN9-to-partner and partner-to-SEPTIN9 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN9→partner) and Y-score (partner→SEPTIN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CPED1 →	+0.868	+0.194	<.001	.002	3	4
UCEC	AHNAK →	+0.709	+0.253	<.001	<.001	3	4
GBM	SCN7A →	+1.419	+0.208	<.001	<.001	3	4
LUAD	FN3KRP →	+0.655	+0.221	<.001	<.001	3	4
LSCC	PDCD11 →	-0.424	-0.121	.001	.004	3	4
LSCC	TGFBR2 →	+0.655	+0.140	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,126 associations by consensus.

Exploration

SEPTIN9 survival (RNA) · tumor vs normal (RNA) · all SEPTIN9 data types