Across TCGA patient cohorts, SEPTIN9 mutation is significantly associated with the RNA expression of many other genes, with 2,894 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SEPTIN9-associated genes across cancer lineages are RNU6-1318P, FEN1, and OSBP. Each is linked with SEPTIN9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SEPTIN9-to-partner and partner-to-SEPTIN9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN9→partner) and Y-score (partner→SEPTIN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1318P →	+0.146	+1.844	.003	.003	3	3
SKCM	FEN1 →	+0.523	+2.228	.005	.006	3	3
COAD	OSBP →	+0.360	+3.371	.005	.004	3	3
UCEC	ARNTL →	+0.318	+1.279	<.001	.003	3	3
COAD	MFAP1 →	+0.460	+3.740	.002	<.001	3	3
COAD	MESD →	+0.511	+2.638	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,894 associations by consensus.

Exploration

SEPTIN9 survival (RNA) · tumor vs normal (RNA) · all SEPTIN9 data types