SEPTIN7P4

Across TCGA pan-cancer cohorts, SEPTIN7P4 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated SEPTIN7P4 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher SEPTIN7P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SEPTIN7P4 expression acts as an unfavorable survival marker.

LIHC, SARC, and LUSC are the cancer types where SEPTIN7P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	III,IV	0.051	0.650	<.001	36	view →
SARC	OS	Tertile	All	0.164	0.778	<.001	21	view →
LUSC	OS	Tertile	II,III,IV	0.449	0.735	.006	18	view →
LGG	OS	Tertile	All	0.612	0.815	.023	9	view →
TGCT	DFS	Tertile	All	0.234	0.678	.037	6	view →
GBM	DFS	Quartile	All	0.180	0.359	.025	3	view →
KICH	DFS	Tertile	All	0.425	0.847	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SEPTIN7P4–LIHC (OS)

Open the LIHC breakdown →